Please use this identifier to cite or link to this item: https://doi.org/10.1046/j.1365-2044.2001.02059-6.x
Title: Effect of ondansetron pretreatment on pain after rocuronium and propofol injection: A randomised, double-blind controlled comparison with lidocaine
Authors: Reddy, M.S.
Chen, F.-G. 
Ng, H.-P.
Keywords: Anaesthetics, intravenous: propofol
Anti-emetics: ondansetron
Complications: pain
Neuromuscular non-depolarising agents: rocuronium
Issue Date: 2001
Citation: Reddy, M.S., Chen, F.-G., Ng, H.-P. (2001). Effect of ondansetron pretreatment on pain after rocuronium and propofol injection: A randomised, double-blind controlled comparison with lidocaine. Anaesthesia 56 (9) : 902-905. ScholarBank@NUS Repository. https://doi.org/10.1046/j.1365-2044.2001.02059-6.x
Abstract: In a randomised, controlled, double-blinded trial to study the effect of ondansetron pretreatment on the pain produced after intravenous injection of rocuronium and propofol in comparison with lidocaine, 60 patients were randomly assigned to one of three groups. Group 1 received 5 ml of intravenous 0.9% sodium chloride solution pretreatment, group 2 received ondansetron 4 mg (2 mg.ml -1 solution) diluted into a 5-ml solution, and group 3 received 50 mg lidocaine (5 ml 1% solution); this was followed 1 min later by rocuronium and propofol. Pain was reduced significantly in the ondansetron and lidocaine groups (p < 0.0001) compared with placebo, and significantly better with lidocaine than with ondansetron (p = 0.02). We conclude that ondansetron is effective in relieving the pain of rocuronium but is not as effective as lidocaine.
Source Title: Anaesthesia
URI: http://scholarbank.nus.edu.sg/handle/10635/129515
ISSN: 00032409
DOI: 10.1046/j.1365-2044.2001.02059-6.x
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

54
checked on May 21, 2018

WEB OF SCIENCETM
Citations

39
checked on Apr 24, 2018

Page view(s)

12
checked on May 10, 2018

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.