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Title: Epstein-Barr viral antigens used in the diagnosis of nasopharyngeal carcinoma
Authors: Gan, Y.Y.
Fones-Tan, A.
Chan, S.H. 
Gan, L.H.
Keywords: Antibodies
Epstein-Barr virus
Nasopharyngeal carcinoma
Issue Date: 1996
Source: Gan, Y.Y.,Fones-Tan, A.,Chan, S.H.,Gan, L.H. (1996). Epstein-Barr viral antigens used in the diagnosis of nasopharyngeal carcinoma. Journal of Biomedical Science 3 (3) : 159-169. ScholarBank@NUS Repository.
Abstract: The major antigen complexes of Epstein-Barr virus (EBV) include the latent infectious proteins, early antigens, membrane antigens and viral capsid antigens. The various polypeptides within each antigen complex have been identified and isolated through gene-cloning technology. These polypeptides are exploited to be used as serological markers for the diagnosis of nasopharyngeal carcinoma (NPC) through enzyme-linked immunosorbent assay. This paper reviews the recent studies on the profile of antibodies in patients with NPC towards these EBV polypeptides of each antigen complex. The sensitivity and specificity of each polypeptide when used as serological markers to NPC patients' sera are summarized.
Source Title: Journal of Biomedical Science
ISSN: 10217770
Appears in Collections:Staff Publications

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