Please use this identifier to cite or link to this item: https://doi.org/10.1111/1748-5967.12011
Title: Enhanced activities of reproductive system in male rat treated with male silkworm pupae extract
Authors: Kwon, M.-G.
Kim, D.-S.
Lee, J.-H.
Park, S.-R.
Ahn, J.
Kim, J.-S.
Ko, K.
Park, S. 
Kang, Y.-S.
Choo, Y.-K.
Ko, K.
Keywords: Nuegra
Phospholipid-hydroperoxide glutathione peroxidase
Silkworm pupae extract
Sperm
Issue Date: Mar-2013
Citation: Kwon, M.-G., Kim, D.-S., Lee, J.-H., Park, S.-R., Ahn, J., Kim, J.-S., Ko, K., Park, S., Kang, Y.-S., Choo, Y.-K., Ko, K. (2013-03). Enhanced activities of reproductive system in male rat treated with male silkworm pupae extract. Entomological Research 43 (2) : 101-107. ScholarBank@NUS Repository. https://doi.org/10.1111/1748-5967.12011
Abstract: A male silkworm pupae extract with herbal mixtures such as Rubus coreanusMiquel, Chinese matrimony vine Acanthopanax senticosus and tocopherol can be effectively used to recover or boost stamina. In this study, the effect of the male silkworm pupae extract on the reproductive system of Sprague-Dawley male rats was investigated. No clinical symptoms, and no dying or dead animals were found among experimental male silkworm larvae extract, male silkworm pupae extract and control rat groups during the study. No significant differences were found in body weights, feed or water consumption, or macroscopic examination among the three groups. No lesion was found upon necropsy. However, sperm in the group treated with male silkworm pupae extract were significantly more active than sperm in the control group. Sperm counts in both male groups treated with male silkworm larvae extract and male silkworm pupae extract were significantly higher than sperm counts in the control group. Analysis of phospholipid-hydroperoxide glutathione peroxidase (PHGPx) gene expression showed that the male silkworm pupae extract increased expression in testes by 26.7%. This study shows that the male silkworm pupae extract has potential to be used to enhance the function of the human reproductive system. © 2013 The Entomological Society of Korea and Wiley Publishing Asia Pty Ltd.
Source Title: Entomological Research
URI: http://scholarbank.nus.edu.sg/handle/10635/128523
ISSN: 17382297
DOI: 10.1111/1748-5967.12011
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