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|Title:||Unfractionated heparin versus low-molecular-weight heparin for avoiding heparin-induced thrombocytopenia in postoperative patients|
low molecular weight heparin
|Citation:||Ang, E. (2013-09). Unfractionated heparin versus low-molecular-weight heparin for avoiding heparin-induced thrombocytopenia in postoperative patients. Clinical Nurse Specialist 27 (5) : 229-230. ScholarBank@NUS Repository. https://doi.org/10.1097/NUR.0b013e3182a0ba2b|
|Abstract:||Results fromthe 2 trials indicated that patients given LMWH had a statistically significant lower risk of HIT than did those given UFH (risk ratio, 0.24; 95% confidence interval, 0.07Y0.82; P = .02). Thus, patients treated with LMWH would have a relative risk reduction of 76% in developing HIT compared with those treated with UFH. The results also showed a statistically significant reduction in HIT complicated VTE in patients receiving LMWH compared with UFH (risk ratio, 0.20; 95% confidence interval, 0.04Y0.90; P = .04; 2 trials). This result indicates that patients treated with LMWH would have a relative risk reduction of 80%in developing HIT complicated VTE compared with those using UFH.One patient treated with UFH had arterial thrombosis, and there were no reports on amputation and death.|
|Source Title:||Clinical Nurse Specialist|
|Appears in Collections:||Staff Publications|
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