Please use this identifier to cite or link to this item:
https://scholarbank.nus.edu.sg/handle/10635/127074
Title: | Optimising the management of choroidal neovascularisation in Asian patients: consensus on treatment recommendations for anti-VEGF therapy | Authors: | Koh, A. Lim, T.H. Au Eong, K.G. Chee, C. Ong, S.G. Tan, N. Yeo, I. Wong, D. |
Keywords: | Age-related macular degeneration Choroidal neovascularisation Monoclonal antibody Ranibizumab |
Issue Date: | Apr-2011 | Abstract: | In Asian countries, age-related macular degeneration (AMD), specifically wet AMD or choroidal neovascularisation (CNV), is an important cause of blindness and visual handicap. Vascular endothelial growth factors (VEGF) play an integral role in the development of CNV and thus provide an important therapeutic target. Current treatment paradigms for neovascular AMD recognise the place of photodynamic therapy (PDT) in the management of this condition. However, combination therapy targeting different pathways to produce a synergistic effect may result in improved visual outcomes and reduced duration of treatment. Anti-VEGF therapy hasgreatly improved treatment outcomes in patients with CNV, and a growing body of evidence supports the role of these agents as monotherapy or in combination with PDT. In particular, anti-VEGF may be a first-line treatment option in certain types of subfoveal myopic CNV as well as for classic and occult juxtafoveal and subfoveal CNV. The implementation of evidence-based medicine into current clinical practice is paramount to improving patient care. The authors, who are also members of the Singapore Medical Retina Advisory Board, outline the consensus points and recommended treatment algorithms based on currently available knowledge to provide a structured management approach to the treatment of Asian patients with CNV. | Source Title: | Singapore Medical Journal | URI: | http://scholarbank.nus.edu.sg/handle/10635/127074 | ISSN: | 00375675 |
Appears in Collections: | Staff Publications |
Show full item record
Files in This Item:
There are no files associated with this item.
Google ScholarTM
Check
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.