Please use this identifier to cite or link to this item:
|Title:||Spiradenocarcinoma with low-grade basal cell adenocarcinoma pattern: Report of a case with varied morphology and wild type TP53|
|Authors:||Petersson, F. |
|Citation:||Petersson, F., Nga, M.E. (2012-03). Spiradenocarcinoma with low-grade basal cell adenocarcinoma pattern: Report of a case with varied morphology and wild type TP53. Journal of Cutaneous Pathology 39 (3) : 372-376. ScholarBank@NUS Repository. https://doi.org/10.1111/j.1600-0560.2011.01810.x|
|Abstract:||We present a patient with a 2-cm spiradenocarcinoma of the left arm resembling low-grade salivary gland basal cell adenocarcinoma. In addition to showing attributes of conventional spiradenoma, the benign component showed prominent areas of cystic change with focal apocrine differentiation, glands with and without mucinous differentiation, clear cell change and focal adenoid cystic carcinoma-like areas. The malignant component was composed of nodules of basaloid cells arranged in sheets with variable tendency to luminal differentiation. The nuclear atypia was low-grade, and the mitotic index was high in the malignant component (to 8/10 high power fields). Immunohistochemically, there was diffuse but variable positivity for cytokeratin 7 in both the benign and malignant components. Epithelial membrane antigen was focally positive, highlighting cells with ductal (luminal) differentiation. Expression of p63 was observed in 50 and 80% of the cells in the benign and malignant components, respectively. Calponin was negative. The proliferative index (MIB-1/Ki-67) was|
|Source Title:||Journal of Cutaneous Pathology|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Jul 16, 2018
WEB OF SCIENCETM
checked on May 23, 2018
checked on Mar 11, 2018
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.