Please use this identifier to cite or link to this item: https://doi.org/10.2174/157340010791196475
Title: Molecular biomarkers in schizophrenia - implications for clinical practice
Authors: Lee, J. 
Chong, S.-A.
Keywords: Biomarkers
Epigenomics
Genomics
Lipidomics
Proteomics
Schizophrenia
Issue Date: May-2010
Source: Lee, J., Chong, S.-A. (2010-05). Molecular biomarkers in schizophrenia - implications for clinical practice. Current Psychiatry Reviews 6 (2) : 114-121. ScholarBank@NUS Repository. https://doi.org/10.2174/157340010791196475
Abstract: Schizophrenia is a serious mental illness and clinical diagnosis over the past century had been based on recognition of a certain pattern of thinking, perception and behavior. Although mostly people accept that the disease is a complex phenotypic presentation with a strong hereditary predisposition, the exact pathophysiology of schizophrenia has not been clearly elucidated. Rapid advancements in genomics, epigenomics, transcriptomics, proteomics and lipidomics had been made in the search for molecular biomarkers in schizophrenia which could potentially aid clinicians in understanding and subtyping psychosis. It could assist in diagnosis and selection of appropriate antipsychotic therapy, it also provides early indicators of clinical response. In this review, we discuss relevant literature with regards to these advancements, their challenges and their potential clinical impact. © 2010 Bentham Science Publishers Ltd.
Source Title: Current Psychiatry Reviews
URI: http://scholarbank.nus.edu.sg/handle/10635/124702
ISSN: 15734005
DOI: 10.2174/157340010791196475
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