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Title: Prevalence of comorbidities and baseline characteristics of LAP-BAND AP® subjects in the Helping Evaluate Reduction in Obesity (HERO) study
Authors: Dreyer, N.
Dixon, J.B.
Okerson, T.
Finkelstein, E.A. 
Globe, D.
Issue Date: 15-Nov-2013
Citation: Dreyer, N., Dixon, J.B., Okerson, T., Finkelstein, E.A., Globe, D. (2013-11-15). Prevalence of comorbidities and baseline characteristics of LAP-BAND AP® subjects in the Helping Evaluate Reduction in Obesity (HERO) study. PLoS ONE 8 (11) : -. ScholarBank@NUS Repository.
Abstract: Objective: To describe the baseline characteristics in patients who chose placement of a LAP-BAND AP® System (LBAP) and participated in the Helping Evaluate Reduction in Obesity (HERO) Study across regions. Patients and Methods: HERO is a five- year, prospective, multicenter, international study of patients with LBAP placement between July 22, 2009 and January 31, 2011. In addition to baseline and peri-surgery clinical data, seven follow up visits are scheduled at 3, 6 and 12 months, and annually through year five. Data collection included family and medical history, clinical outcomes, laboratory data, health-related quality of life (HRQoL), productivity, healthcare resource utilization, and adverse events. Results: LBAP were placed in 1106 enrolled patients; 56.6% from the US, 26.3% from Europe, 7.1% from Canada, and 10.0% from Australia. The majority were female (n = 877 (79.3%)) with a mean age of 43 years (s.d. = 11.4) and mean body mass index of 45.1 kg/m2 (s.d. = 6.9). The most common comorbidities were hypertension (HTN) (overall = 42.9%) and diabetes (overall 22.2%, with 27% from the US and 14% from Europe). Overall, less than 5% had a history of cardiovascular disease. The prevalence rates of HTN, diabetes and cardiovascular disease were significantly (p
Source Title: PLoS ONE
ISSN: 19326203
DOI: 10.1371/journal.pone.0078971
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