DEFINING THE MOLECULAR MECHANISMS IN LUMBAR SPINAL FUSION

Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/122490

DC Field	Value
dc.title	DEFINING THE MOLECULAR MECHANISMS IN LUMBAR SPINAL FUSION
dc.contributor.author	HU TAO
dc.date.accessioned	2016-02-12T18:00:14Z
dc.date.available	2016-02-12T18:00:14Z
dc.date.issued	2015-07-28
dc.identifier.citation	HU TAO (2015-07-28). DEFINING THE MOLECULAR MECHANISMS IN LUMBAR SPINAL FUSION. ScholarBank@NUS Repository.
dc.identifier.uri	http://scholarbank.nus.edu.sg/handle/10635/122490
dc.description.abstract	DELIVERY OF LOW DOSE RHBMP-2 BY PEC WAS ABLE TO ACHIEVE SOLID SPINAL FUSION IN LUMBAR SPINAL FUSION MODEL. THIS BONE-INDUCTIVE SYSTEM REDUCED THE ADVERSE EFFECTS SUCH AS SEROMA FORMATION AND ECTOPIC BONE FORMATION, NORMALLY ASSOCIATED WITH SUPRAPHYSIOLOGICAL DOSES OF RHBMP-2 AS SEEN IN CLINICAL PRACTICE. IT HAS THE POTENTIAL FOR USE IN SPINAL FUSION APPLICATIONS AND OTHER BONE TISSUE ENGINEERING PROCEDURES.
dc.language.iso	en
dc.subject	spinal fusion chamber, spine, bone morphogenetic protein, gene expression, collagen expression
dc.type	Thesis
dc.contributor.department	ORTHOPAEDIC SURGERY
dc.contributor.supervisor	WONG HEE KIT
dc.contributor.supervisor	GOH CHO HONG, JAMES
dc.description.degree	Ph.D
dc.description.degreeconferred	DOCTOR OF PHILOSOPHY
dc.identifier.isiut	NOT_IN_WOS
Appears in Collections:	Ph.D Theses (Open)

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