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https://scholarbank.nus.edu.sg/handle/10635/122490
| Title: | DEFINING THE MOLECULAR MECHANISMS IN LUMBAR SPINAL FUSION | Authors: | HU TAO | Keywords: | spinal fusion chamber, spine, bone morphogenetic protein, gene expression, collagen expression | Issue Date: | 28-Jul-2015 | Citation: | HU TAO (2015-07-28). DEFINING THE MOLECULAR MECHANISMS IN LUMBAR SPINAL FUSION. ScholarBank@NUS Repository. | Abstract: | DELIVERY OF LOW DOSE RHBMP-2 BY PEC WAS ABLE TO ACHIEVE SOLID SPINAL FUSION IN LUMBAR SPINAL FUSION MODEL. THIS BONE-INDUCTIVE SYSTEM REDUCED THE ADVERSE EFFECTS SUCH AS SEROMA FORMATION AND ECTOPIC BONE FORMATION, NORMALLY ASSOCIATED WITH SUPRAPHYSIOLOGICAL DOSES OF RHBMP-2 AS SEEN IN CLINICAL PRACTICE. IT HAS THE POTENTIAL FOR USE IN SPINAL FUSION APPLICATIONS AND OTHER BONE TISSUE ENGINEERING PROCEDURES. | URI: | http://scholarbank.nus.edu.sg/handle/10635/122490 |
| Appears in Collections: | Ph.D Theses (Open) |
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| HUTao.pdf | 2.07 MB | Adobe PDF | OPEN | None | View/Download |
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