Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/119273
Title: Genomic Analysis Using Short Sequencing Tags
Authors: CHANG CHENG WEI
Keywords: chipseq, cofactor, prediction
Issue Date: 30-Jul-2014
Source: CHANG CHENG WEI (2014-07-30). Genomic Analysis Using Short Sequencing Tags. ScholarBank@NUS Repository.
Abstract: ChIP-seq is a revolutionary assay used to detect the binding sites of TF in the entire genome, made possible through the rapid advancement in high-throughput sequencing technology. The precision of the binding location of TF can be detected within positional accuracy of +/-200 bp. Motif predictions of TF binding sites tend to yield a much greater accuracy when restricted to regions near ChIP-seq peaks. This thesis studies the problems related to prediction of cofactors by taking advantage of the high resolution of the technology.
URI: http://scholarbank.nus.edu.sg/handle/10635/119273
Appears in Collections:Ph.D Theses (Open)

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