Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/119031
Title: REAL-TIME MONITORING OF PROBE-TISSUE PRESSURE EFFECTS ON IN VIVO SKIN OPTICAL SPECTROSCOPY USING A PRESSURE SENSITIVE FIBEROPTIC PROBE
Authors: ARNOLD JULIAN VINOJ BENJAMIN
Keywords: probe-tissue contact pressure, optical spectroscopy, pressure sensitive probe,in vivo skin measurements, multivariate statistical analysis
Issue Date: 18-Aug-2014
Source: ARNOLD JULIAN VINOJ BENJAMIN (2014-08-18). REAL-TIME MONITORING OF PROBE-TISSUE PRESSURE EFFECTS ON IN VIVO SKIN OPTICAL SPECTROSCOPY USING A PRESSURE SENSITIVE FIBEROPTIC PROBE. ScholarBank@NUS Repository.
Abstract: A NOVEL PROBE DESIGN IS PRESENTED FOR REAL-TIME MONITORING OF PROBE-TISSUE CONTACT PRESSURE EFFECTS DURING IN VIVO SKIN OPTICAL SPECTROSCOPY MEASUREMENTS. THE DEVELOPED PRESSURE SENSITIVE PROBE IS VITAL TO PRESERVE IMPORTANT DIAGNOSTIC INFORMATION THAT MAY BE LOST DUE TO EXCESSIVE PROBE PRESSURE. OPTICAL SPECTRA WERE ACQUIRED DURING IN VIVO AUTOFLUORESCENCE (AF), DIFFUSE REFLECTANCE (DR) AND RAMAN SPECTROSCOPIC MEASUREMENTS ON HUMAN SKIN SITES (I.E. INDEX FINGERTIP, PALM AND VOLAR FOREARM) AT DIFFERENT PROBE-TISSUE CONTACT PRESSURES TO EVALUATE THE PROBE PRESSURE INDUCED VARIATIONS IN THE ACQUIRED SPECTRAL DATA. MULTIVARIATE STATISTICAL ANALYSIS WAS PERFORMED ON THE ACQUIRED SPECTRA TO ESTIMATE THE DIAGNOSTIC IMPORTANCE OF PROBE PRESSURE INDUCED VARIATIONS ON THE SPECTRAL DATA. THE RESULTS SHOW THAT PROBE PRESSURE IS AN ESSENTIAL PARAMETER THAT AFFECTS THE OPTICAL SPECTRA SIGNIFICANTLY. PROBE PRESSURE INDUCED SPECTRAL VARIATIONS CAN BE MITIGATED BY THE UTILIZATION OF THE DEVELOPED PRES
URI: http://scholarbank.nus.edu.sg/handle/10635/119031
Appears in Collections:Master's Theses (Open)

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