Please use this identifier to cite or link to this item:
|Title:||Loperamide-based compounds as additives for biofouling management|
|Citation:||Chai, C.L.L., Teo, S.L.M., Jameson, F.K.M., Lee, S.S.C., Likhitsup, A., Chen, C.-L., Rittschof, D. (2014-04). Loperamide-based compounds as additives for biofouling management. International Biodeterioration and Biodegradation 89 : 82-87. ScholarBank@NUS Repository. https://doi.org/10.1016/j.ibiod.2014.01.003|
|Abstract:||The commercial pharmaceutical Imodium™, which contains the active ingredient loperamide hydrochloride, has been shown to have biofouling control properties. However, due to concerns associated with safety and persistence of this active pharmaceutical ingredient (API) in the environment, the development of loperamide as an anti-fouling additive is not desirable. In this paper, we report our efforts directed towards the design and synthesis of small molecule anti-foulants using the loperamide parent compound as the lead compound. These loperamide-based compounds can be synthesized readily and inexpensively. Several of the compounds identified are potentially useful as additives in marine antifouling coatings as they control attachment of barnacles in laboratory tests and an estimation program (BIOWIN) developed by the US Environmental Protection Agency predicts that they will degrade completely in weeks to months. © 2014 Elsevier Ltd.|
|Source Title:||International Biodeterioration and Biodegradation|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Jan 16, 2019
WEB OF SCIENCETM
checked on Jan 7, 2019
checked on Jan 18, 2019
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.