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|Title:||Serum insulin-like growth factor-I (IGF-I) and dehydroepiandrosterone- sulphate (DHEA-S) in a community dwelling elderly population|
|Source:||Zhou, X.,Hintz, R.L.,Lin, T.-K.,How, W.H.K.,Aw, T.-C.,Lee, K.-O. (1997). Serum insulin-like growth factor-I (IGF-I) and dehydroepiandrosterone- sulphate (DHEA-S) in a community dwelling elderly population. Endocrinology and Metabolism 4 (5) : 345-351. ScholarBank@NUS Repository.|
|Abstract:||Previous studies have reported that both serum insulin-like growth factor I (IGF-I) and dehydroepiandrosterone-sulphate (DHEA-S) decline with ageing, particularly in chronically institutionalized elderly men, with an association with disease morbidity. We measured serum IGF-I and DHEA-S in two groups of ambulatory community dwelling ethnic Chinese of ages 60-99 years: a 'healthy' group of men and women (n=64) without any known illness and an 'unhealthy' group (n=53), still living in the community but with various chronic illnesses. Healthy young ethnic Chinese acted as controls. Serum IGF- II, IGF binding protein-3 (IGFBP-3) and prostate specific antigen (PSA) were also measured. Mean serum IGF-I, DHEA-S, IGF-II and IGFBP-3 were all lower in the elderly compared to the younger controls (P|
|Source Title:||Endocrinology and Metabolism|
|Appears in Collections:||Staff Publications|
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