Please use this identifier to cite or link to this item: https://doi.org/10.1371/journal.pone.0013765
Title: Dopamine D4 receptor gene associated with fairness preference in ultimatum game
Authors: Zhong, S.
Israel, S.
Shalev, I.
Xue, H.
Ebstein, R.P.
Chew, S.H. 
Issue Date: 2010
Citation: Zhong, S., Israel, S., Shalev, I., Xue, H., Ebstein, R.P., Chew, S.H. (2010). Dopamine D4 receptor gene associated with fairness preference in ultimatum game. PLoS ONE 5 (11) : -. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pone.0013765
Abstract: In experimental economics, the preference for reciprocal fairness has been observed in the controlled and incentivized laboratory setting of the ultimatum game, in which two individuals decide on how to divide a sum of money, with one proposing the share while the second deciding whether to accept. Should the proposal be accepted, the amount is divided accordingly. Otherwise, both would receive no money. A recent twin study has shown that fairness preference inferred from responder behavior is heritable, yet its neurogenetic basis remains unknown. The D4 receptor (DRD4) exon3 is a wellcharacterized functional polymorphism, which is known to be associated with attention deficit hyperactivity disorder and personality traits including novelty seeking and self-report altruism. Applying a neurogenetic approach, we find that DRD4 is significantly associated with fairness preference. Additionally, the interaction among this gene, season of birth, and gender is highly significant. This is the first result to link preference for reciprocal fairness to a specific gene and suggests that gene × environment interactions contribute to economic decision making. © 2010 Zhong et al.
Source Title: PLoS ONE
URI: http://scholarbank.nus.edu.sg/handle/10635/114161
ISSN: 19326203
DOI: 10.1371/journal.pone.0013765
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