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|Title:||Monitoring of exposure to cyclohexanone through the analysis of breath and urine|
|Authors:||Ong, C.-N. |
|Source:||Ong, C.-N.,Chia, S.-E.,Phoon, W.-H.,Tan, K.-T.,Kok, P.-W. (1991). Monitoring of exposure to cyclohexanone through the analysis of breath and urine. Scandinavian Journal of Work, Environment and Health 17 (6) : 430-435. ScholarBank@NUS Repository.|
|Abstract:||Occupational exposure to cyclohexanone was studied for 59 workers through the analysis of environmental air, alveolar air, and urinary cyclohexanol. Environmental cyclohexanone exposure was measured by personal sampling with a carbon-felt passive dosimeter. Cyclohexanone in alveolar air and cyclohexanol in urine were determined with gas chromatography with a flame ionization detector. The end-of-shift urinary cyclohexanol levels correlated well with the time-weighted average environmental cyclohexanone values (r = 0.66). Urinary cyclohexanol corrected for creatinine correlated best with cyclohexanone in air (r = 0.77); when corrected for specific gravity, it gave a similar correlation coefficient (r = 0.73). When the time-weighted average of the exposure was 25 ppm, the corresponding calculated concentration for urinary cyclohexanol was 54.5 mg/l, 23.3 mg/g of creatinine, or 43.5 mg/l at a specific gravity of 1.018. The relationship between cyclohexanone exposure and its concentration in exhaled breath was found to be poorer than that for cyclohexanone exposure and the urinary metabolite (r=0.51).|
|Source Title:||Scandinavian Journal of Work, Environment and Health|
|Appears in Collections:||Staff Publications|
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