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Title: Exploitation of physical and chemical constraints for three-dimensional microtissue construction in microfluidics
Authors: Choudhury, D.
Mo, X.
Iliescu, C.
Tan, L.L.
Tong, W.H.
Yu, H. 
Issue Date: 1-Apr-2011
Source: Choudhury, D., Mo, X., Iliescu, C., Tan, L.L., Tong, W.H., Yu, H. (2011-04-01). Exploitation of physical and chemical constraints for three-dimensional microtissue construction in microfluidics. Biomicrofluidics 5 (2) : -. ScholarBank@NUS Repository.
Abstract: There are a plethora of approaches to construct microtissues as building blocks for the repair and regeneration of larger and complex tissues. Here we focus on various physical and chemical trapping methods for engineering three-dimensional microtissue constructs in microfluidic systems that recapitulate the in vivo tissue microstructures and functions. Advances in these in vitro tissue models have enabled various applications, including drug screening, disease or injury models, and cell-based biosensors. The future would see strides toward the mesoscale control of even finer tissue microstructures and the scaling of various designs for high throughput applications. These tools and knowledge will establish the foundation for precision engineering of complex tissues of the internal organs for biomedical applications. © 2011 American Institute of Physics.
Source Title: Biomicrofluidics
ISSN: 19321058
DOI: 10.1063/1.3593407
Appears in Collections:Staff Publications

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