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|Title:||GS28, a 28-kilodalton golgi SNARE that participates in ER-Golgi transport|
|Authors:||Subramaniam, V.N. |
|Citation:||Subramaniam, V.N.,Peter, F.,Philp, R.,Wong, S.H.,Hong, W. (1996-05-24). GS28, a 28-kilodalton golgi SNARE that participates in ER-Golgi transport. Science 272 (5265) : 1161-1163. ScholarBank@NUS Repository.|
|Abstract:||Little is known about the integral membrane proteins that participate in the early secretory pathway of mammalian cells, The complementary DNA encoding a 28-kilodalton protein (p28) of the cis-Golgi was cloned and sequenced. The protein was predicted to contain a central coiled-coil domain with a carboxyl-terminal membrane anchor. An in vitro assay for endoplasmic reticulum-Golgi transport was used to show that p28 participates in the docking and fusion stage of this transport event. Biochemical studies established that p28 is a core component of the Golgi SNAP receptor (SNARE) complex.|
|Appears in Collections:||Staff Publications|
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