Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/111891
Title: From sequence to structure to literature: the protocol approach to bioinformation.
Authors: Wu, O.P.
Seow, K.T. 
Wong, L.
Chung, S.Y.
Subbiah, S.
Issue Date: 1998
Citation: Wu, O.P.,Seow, K.T.,Wong, L.,Chung, S.Y.,Subbiah, S. (1998). From sequence to structure to literature: the protocol approach to bioinformation.. Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing : 747-758. ScholarBank@NUS Repository.
Abstract: Until the recent advent of high-throughput experimental data-acquisition in biology, the computational analysis of the biological data was predominantly on an ad hoc basis--i.e., the application of a given piece of software on the biological data depended on the need of the moment. This "functional approach" often resulted in piecemeal computational analysis with large amount of intervening "dead-time". The present high-throughput availability of experimental biological data requires a more streamlined and integrated "protocol approach". In this work, we illustrate such a user-friendly protocol using a common question frequently faced by a wet-lab bench-biologist--"Now that I have a DNA or protein sequence, what can I do with it using a computer?" As phrased, this question is steeped in the functional approach. In contrast, the protocol approach would re-phrase the same question as "Now that I have a DNA or protein sequence, what can a computer do for me?" Our integrating tool can start with a sequence and build a substantial custom data-warehouse of computationally derived sequence information, structure information and relevant published literature, that is continually updated.
Source Title: Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
URI: http://scholarbank.nus.edu.sg/handle/10635/111891
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

Page view(s)

37
checked on Oct 12, 2018

Google ScholarTM

Check


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.