Please use this identifier to cite or link to this item:
|Title:||Genetic contributions to myopic refractive error: Insights from human studies and supporting evidence from animal models|
|Citation:||Hawthorne, F.A., Young, T.L. (2013-09). Genetic contributions to myopic refractive error: Insights from human studies and supporting evidence from animal models. Experimental Eye Research 114 : 141-149. ScholarBank@NUS Repository. https://doi.org/10.1016/j.exer.2012.12.015|
|Abstract:||Genetic studies of both population-based and recruited affected patient cohorts have identified a number of genomic regions and candidate genes that may contribute to myopic development. Scientists have developed animal models of myopia, as collection of affected tissues from patents is impractical. Recent advances in whole exome sequencing technology show promise for further elucidation of disease causing variants as in the recent identification of rare variants within ZNF644 segregating with pathological myopia. We present a review of the current research trends and findings on genetic contributions to myopic refraction including candidate loci for myopic development and their genomic convergence with expression studies of animal models inducing myopic development. © 2013 .|
|Source Title:||Experimental Eye Research|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on May 20, 2018
WEB OF SCIENCETM
checked on Apr 23, 2018
checked on Mar 12, 2018
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.