Please use this identifier to cite or link to this item:
https://doi.org/10.1016/j.vaccine.2010.10.046
DC Field | Value | |
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dc.title | Opsonophagocytic activity following a reduced dose 7-valent pneumococcal conjugate vaccine infant primary series and 23-valent pneumococcal polysaccharide vaccine at 12 months of age | |
dc.contributor.author | Russell, F.M. | |
dc.contributor.author | Carapetis, J.R. | |
dc.contributor.author | Burton, R.L. | |
dc.contributor.author | Lin, J. | |
dc.contributor.author | Licciardi, P.V. | |
dc.contributor.author | Balloch, A. | |
dc.contributor.author | Tikoduadua, L. | |
dc.contributor.author | Waqatakirewa, L. | |
dc.contributor.author | Cheung, Y.B. | |
dc.contributor.author | Tang, M.L.K. | |
dc.contributor.author | Nahm, M.H. | |
dc.contributor.author | Mulholland, E.K. | |
dc.date.accessioned | 2014-11-26T08:29:41Z | |
dc.date.available | 2014-11-26T08:29:41Z | |
dc.date.issued | 2011-01-10 | |
dc.identifier.citation | Russell, F.M., Carapetis, J.R., Burton, R.L., Lin, J., Licciardi, P.V., Balloch, A., Tikoduadua, L., Waqatakirewa, L., Cheung, Y.B., Tang, M.L.K., Nahm, M.H., Mulholland, E.K. (2011-01-10). Opsonophagocytic activity following a reduced dose 7-valent pneumococcal conjugate vaccine infant primary series and 23-valent pneumococcal polysaccharide vaccine at 12 months of age. Vaccine 29 (3) : 535-544. ScholarBank@NUS Repository. https://doi.org/10.1016/j.vaccine.2010.10.046 | |
dc.identifier.issn | 0264410X | |
dc.identifier.uri | http://scholarbank.nus.edu.sg/handle/10635/110199 | |
dc.description.abstract | Opsonophagocytic activity (OPA) was measured following reduced infant doses of 7-valent pneumococcal conjugate vaccine (PCV-7) with or without 23-valent pneumococcal polysaccharide vaccine (PPV-23) at 12 months, and subsequent re-exposure to a small dose of pneumococcal polysaccharide antigens (mPPS) at 17 months. Fijian infants were randomized to receive 0, 1, 2, or 3 PCV-7 doses. Half received PPV-23 at 12 months and all received mPPS at 17 months. OPA was performed on up to 14 serotypes. Three and 2 PCV-7 doses resulted in similar OPA for most PCV-7 serotypes up to 9 months and for half of the serotypes at 12 months. A single dose improved OPA compared with the unvaccinated group. PPV-23 significantly improved OPA for all serotypes tested but in general, was associated with diminished responses following re-challenge. © 2010 Elsevier Ltd. | |
dc.description.uri | http://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/j.vaccine.2010.10.046 | |
dc.source | Scopus | |
dc.subject | Opsonophagocytic activity | |
dc.subject | Pneumococcal vaccination | |
dc.type | Article | |
dc.contributor.department | DUKE-NUS GRADUATE MEDICAL SCHOOL S'PORE | |
dc.description.doi | 10.1016/j.vaccine.2010.10.046 | |
dc.description.sourcetitle | Vaccine | |
dc.description.volume | 29 | |
dc.description.issue | 3 | |
dc.description.page | 535-544 | |
dc.description.coden | VACCD | |
dc.identifier.isiut | 000286853200024 | |
Appears in Collections: | Staff Publications |
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