Please use this identifier to cite or link to this item: https://doi.org/10.1371/journal.pone.0049596
Title: Differentiating Non-Motor Symptoms in Parkinson's Disease from Controls and Hemifacial Spasm
Authors: Yong, M.-H.
Allen Jr., J.C.
Prakash, K.M.
Tan, E.-K. 
Issue Date: 11-Feb-2013
Source: Yong, M.-H., Allen Jr., J.C., Prakash, K.M., Tan, E.-K. (2013-02-11). Differentiating Non-Motor Symptoms in Parkinson's Disease from Controls and Hemifacial Spasm. PLoS ONE 8 (2) : -. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pone.0049596
Abstract: Background and Aims: Non-motor symptoms (NMS) are important manifestations of Parkinson's disease (PD) that reduce patients' health-related quality of life. Some NMS may also be caused by age-related changes, or manifested as a psychological reaction to a chronic neurological condition. This case-control study compared the NMS burden among PD patients, healthy controls and hemifacial spasm (HFS) patients. In addition, we determined the NMS that discriminated between PD and non-PD subjects. Methods: 425 subjects were recruited from a tertiary hospital in Singapore (200 PD patients, 150 healthy controls and 75 HFS patients). NMS burden in subjects was measured using the Non-Motor Symptoms Scale (NMSS). Results: NMSS total score was significantly higher in PD patients (37.9±2.6) compared to healthy controls (11.2±0.9) (p
Source Title: PLoS ONE
URI: http://scholarbank.nus.edu.sg/handle/10635/110025
ISSN: 19326203
DOI: 10.1371/journal.pone.0049596
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