Please use this identifier to cite or link to this item: https://doi.org/10.2147/OPTH.S42266
Title: Comparison of corneal sensitivity, tear function and corneal staining following laser in situ keratomileusis with two femtosecond laser platforms
Authors: Petznick, A.
Chew, A.
Hall, R.C.
Chan, C.M.L.
Rosman, M.
Tan, D.
Tong, L. 
Mehta, J.S. 
Keywords: Corneal sensitivity
Corneal staining
Femtosecond laser
Schirmer's
Tear film break-up time
Issue Date: 22-Mar-2013
Citation: Petznick, A., Chew, A., Hall, R.C., Chan, C.M.L., Rosman, M., Tan, D., Tong, L., Mehta, J.S. (2013-03-22). Comparison of corneal sensitivity, tear function and corneal staining following laser in situ keratomileusis with two femtosecond laser platforms. Clinical Ophthalmology 7 : 591-598. ScholarBank@NUS Repository. https://doi.org/10.2147/OPTH.S42266
Abstract: Purpose: To evaluate longitudinal changes in corneal sensitivity, tear function, and corneal staining in patients who underwent laser in situ keratomileusis (LASIK) using two different femtosecond lasers. Methods: In a prospective, randomized clinical trial, contralateral eyes of 45 patients underwent flap creation by either VisuMax or IntraLase™ femtosecond laser. Corneal sensitivity, tear break up time (TBUT), Schirmer's test, and corneal fluorescein staining were assessed preoperatively and at 1 week, 1 month, and 3 months postoperatively. Results: There were no statistical differences in any clinical outcome measure between the two femtosecond lasers (P > 0.05), although there was a trend towards slightly lower reductions for corneal sensitivity and TBUT in VisuMax-operated eyes. Overall, corneal sensitivity was significantly reduced at 1 week (P < 0.05), 1 month (P < 0.001), and 3 months (P < 0.001) postoperatively. A significantly greater reduction of corneal sensitivity was noted in eyes with a myopic spherical equivalent of -6.00 diopters (D) to -11.25 D as compared with eyes that had a relatively lower level of myopia of less than -6.00 D (P < 0.001). TBUT and Schirmer's test values were significantly diminished at 1 week postoperatively (P < 0.04). Overall, corneal staining was significantly increased at 1 week postoperatively (P < 0.001). The level of myopia did not significantly affect postoperative changes in TBUT, Schirmer's test values, or corneal staining (P > 0.05). Conclusion: This study showed that changes in corneal sensitivity, tear function, and corneal staining were statistically similar in LASIK using VisuMax and IntraLase femtosecond lasers for flap creation. However, the trend towards faster recovery of corneal sensitivity and TBUT observed in VisuMax-operated eyes may be attributable to improved technical specifications. © 2013 Petznick et al, publisher and licensee Dove Medical Press Ltd.
Source Title: Clinical Ophthalmology
URI: http://scholarbank.nus.edu.sg/handle/10635/109975
ISSN: 11775467
DOI: 10.2147/OPTH.S42266
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

7
checked on Jul 14, 2018

WEB OF SCIENCETM
Citations

8
checked on Jul 4, 2018

Page view(s)

51
checked on Jun 1, 2018

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.