Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.preteyeres.2007.12.001
Title: Diabetic retinopathy and systemic vascular complications
Authors: Cheung, N.
Wong, T.Y. 
Keywords: Cardiovascular disease prediction
Complications
Coronary heart disease
Heart failure
Macrovascular disease
Microvascular disease
Mortality
Nephropathy
Retinopathy
Stroke
Issue Date: Mar-2008
Citation: Cheung, N., Wong, T.Y. (2008-03). Diabetic retinopathy and systemic vascular complications. Progress in Retinal and Eye Research 27 (2) : 161-176. ScholarBank@NUS Repository. https://doi.org/10.1016/j.preteyeres.2007.12.001
Abstract: Retinopathy is the most common complication of diabetes. The assessment of retinopathy signs presents clinicians a unique opportunity to directly visualize and assess the actual morphology of diabetic microvascular damage. Extensive studies have now shown that people with diabetic retinopathy have excess risks of systemic vascular complications, including subclinical and clinical stroke, coronary heart disease, heart failure, and nephropathy. There is also emerging evidence to suggest that diabetic retinopathy may share common genetic linkages with systemic vascular complications. The extant literature, therefore, supports the theory that diabetic retinopathy reflects widespread microcirculatory disease not only in the eye but also vital organs elsewhere in the body. Being a uniquely specific and non-invasively assessable measure of diabetic microvascular damage, retinopathy may also be envisioned as a novel biomarker of vascular disease risk in asymptomatic patients with diabetes. This review summarizes recent studies on the systemic associations of diabetic retinopathy, and discusses their pathophysiological significance and clinical implications. © 2007 Elsevier Ltd. All rights reserved.
Source Title: Progress in Retinal and Eye Research
URI: http://scholarbank.nus.edu.sg/handle/10635/109834
ISSN: 13509462
DOI: 10.1016/j.preteyeres.2007.12.001
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