Please use this identifier to cite or link to this item:
|Title:||Retinopathy signs in people without diabetes: The multi-ethnic study of atherosclerosis|
|Source:||Ojaimi, E., Nguyen, T.T., Klein, R., Islam, F.M.A., Cotch, M.F., Klein, B.E.K., Wang, J.-J., Wong, T.Y. (2011-04). Retinopathy signs in people without diabetes: The multi-ethnic study of atherosclerosis. Ophthalmology 118 (4) : 656-662. ScholarBank@NUS Repository. https://doi.org/10.1016/j.ophtha.2010.08.007|
|Abstract:||Objective: To describe the prevalence of retinopathy and associations with cardiovascular risk factors in persons without diabetes in 4 racial/ethnic groups (white, black, Hispanic, and Chinese). Design: Population-based, cross-sectional study. Participants: We included 6176 subjects aged 45-84 years without diabetes, selected from 6 United States communities. Methods: Fundus images were taken using 45° digital camera through dark-adapted pupils and were graded for retinopathy as defined by the Early Treatment Diabetic Retinopathy Study severity scale: microaneurysms, hemorrhages, cotton wool spots, intraretinal microvascular abnormalities, hard exudates, venous beading, and new vessels. Main Outcome Measures: Retinopathy and the association with cardiovascular risk factors. Results: Prevalence rates of retinopathy in persons without diabetes were 12.5% overall, varying from 11.9% (white), 13.9% (black), 12.6% (Hispanic), to 17.2% (Chinese). Hypertension was strongly associated with retinopathy (odds ratio [OR], 1.47; 95% confidence interval [CI], 1.23-1.75). After adjusting for age, gender, race, and other parameters, smoking (OR, 1.50; 95% CI, 1.09-2.06) and increased internal carotid intima media thickness (OR, 1.22; 95% CI, 1.05-1.41) were associated with retinopathy. A range of serum inflammatory factors were examined, but none were found to be significant. Conclusions: Retinopathy in persons without diabetes is common, varies with race/ethnicity, and associated with cardiovascular risk factors, including hypertension, smoking, and carotid artery intima media thickness. Financial Disclosure(s): The authors have no proprietary or commercial interest in any of the materials discussed in this article. © 2011 American Academy of Ophthalmology.|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Mar 13, 2018
WEB OF SCIENCETM
checked on Mar 13, 2018
checked on Mar 11, 2018
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.