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Title: Corneal arcus is a sign of cardiovascular disease, even in low-risk persons
Authors: Ang, M.
Wong, W.
Park, J.
Wu, R.
Lavanya, R.
Zheng, Y.
Cajucom-Uy, H.
Tai, E.S.
Wong, T.Y. 
Issue Date: Nov-2011
Citation: Ang, M., Wong, W., Park, J., Wu, R., Lavanya, R., Zheng, Y., Cajucom-Uy, H., Tai, E.S., Wong, T.Y. (2011-11). Corneal arcus is a sign of cardiovascular disease, even in low-risk persons. American Journal of Ophthalmology 152 (5) : 864-871.e1. ScholarBank@NUS Repository.
Abstract: Purpose: To examine the association of corneal arcus to cardiovascular disease (CVD) in an adult, ethnic Indian population. Design: Population-based cross-sectional study. Methods: Population-based study of ethnic South Asian Indians 40 to 80 years of age in Singapore from June 2007 through March 2009. We obtained a 75.5% response rate (3397/4497). All participants underwent standardized interview and systemic and ocular examinations, followed by nonfasting blood sampling. Corneal arcus was detected using a standardized slit-lamp examination. The main outcome measure was CVD, defined from a self-reported history of previous myocardial infarction, angina, or stroke. Results: Corneal arcus, found in 1701 (50.1%) of 3397 participants, was associated with older age (odds ratio [OR], 3.07; 95% CI, 2.78 to 3.40; P
Source Title: American Journal of Ophthalmology
ISSN: 00029394
DOI: 10.1016/j.ajo.2011.04.014
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