Breast cancer in a multi-ethnic Asian setting: Results from the Singapore-Malaysia hospital-based breast cancer registry
Bhoo Pathy, N. Yip, C.H. Taib, N.A. Hartman, M. Saxena, N. Iau, P. Bulgiba, A.M. Lee, S.C. Lim, S.E. Wong, J.E.L.
Bhoo Pathy, N.
Yip, C.H.
Taib, N.A.
Saxena, N.
Iau, P.
Bulgiba, A.M.
Lee, S.C.
Lim, S.E.
Wong, J.E.L.
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Alternative Title
Abstract
Two hospital-based breast cancer databases (University Malaya Medical Center, Malaysia [. n = 1513] and National University Hospital, Singapore [. n = 2545]) were merged into a regional registry of breast cancer patients diagnosed between 1990 and 2007. A review of the data found 51% of patients diagnosed before the age of 50 years. and 72% percent of the women were Chinese followed by Malays (16%), Indians (8%), and other races (4%). Median tumor size at presentation was 26 mm and about 25% of patients presented with TNM stage III or IV disease. Most tumors were of ductal histology (87%). Fifty-seven percent of tumors were estrogen receptor positive and 40% were poorly differentiated. Of those patients who had surgery, 70% had mastectomy while 30% had breast conserving surgery. Overall, chemotherapy was administered to 56% of patients and hormonal treatment to 60%. Five-year overall survival was 82.5% in patients with TNM stage 0 to stage II cancer, and 30.2% in those with later stages. © 2011 Elsevier Ltd.
Keywords
Asia, Asian, Breast cancer, Cancer registry
Source Title
Breast
Publisher
Series/Report No.
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Date
2011-04
DOI
10.1016/j.breast.2011.01.015
Type
Article