Please use this identifier to cite or link to this item: https://doi.org/10.1093/chromsci/bmt057
Title: Multidimensional information-based HPLC technologies to evaluate traditional Chinese medicine
Authors: Yang, D.-Z.
Yin, X.-X.
Ong, C.-N. 
Tang, D.-Q.
Issue Date: Aug-2013
Citation: Yang, D.-Z., Yin, X.-X., Ong, C.-N., Tang, D.-Q. (2013-08). Multidimensional information-based HPLC technologies to evaluate traditional Chinese medicine. Journal of Chromatographic Science 51 (7) : 716-725. ScholarBank@NUS Repository. https://doi.org/10.1093/chromsci/bmt057
Abstract: Traditional Chinese medicines (TCMs) are usually complex mixtures and contain hundreds of chemically different constituents, which make the quality control (QC) of crude drugs and their medical preparations extremely difficult. In the past years, with the rapid development of modern instrumental analysis and computer-aided data processing techniques, great progress has been made in the research of quality standards and the development of QC techniques. Among them, the use of the high-performance liquid chromatography (HPLC) technique is one of the best approaches because of its high separation efficiency. However, one-way separation, single detection methods or data processing cannot meet the needs of the QC of TCMs. Multidimensional information-based HPLC technologies such as two-dimensional HPLC, HPLC coupled with several different detection methods and HPLC fingerprint combined with multicomponent quantification have solved this problem with their comprehensive analysis; these methods have gradually been accepted by more researchers for further in-depth study. The present work provides an overview of the development of QC for TCMs based on HPLC technologies with modern hyphenated techniques, multiseparation methods and some common data processing methods in fingerprint spectra over the last six years. © [2013] The Author.
Source Title: Journal of Chromatographic Science
URI: http://scholarbank.nus.edu.sg/handle/10635/109118
ISSN: 00219665
DOI: 10.1093/chromsci/bmt057
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

7
checked on Jun 15, 2018

WEB OF SCIENCETM
Citations

9
checked on May 23, 2018

Page view(s)

41
checked on Feb 25, 2018

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.