Please use this identifier to cite or link to this item: https://doi.org/10.1111/ceo.12112
Title: Validity of a new optic disc grading software for use in clinical and epidemiological research
Authors: Tham, Y.-C.
Cheung, C.Y. 
Wong, T.Y. 
Baskaran, M.
Liu, J.
Lee, B.-H.
Yin, F.
Wong, D.W.
Wang, J.J.
Mitchell, P.
Aung, T.
Cheng, C.-Y. 
Keywords: Epidemiology
Optic disc
Optic nerve evaluation
Issue Date: Dec-2013
Citation: Tham, Y.-C., Cheung, C.Y., Wong, T.Y., Baskaran, M., Liu, J., Lee, B.-H., Yin, F., Wong, D.W., Wang, J.J., Mitchell, P., Aung, T., Cheng, C.-Y. (2013-12). Validity of a new optic disc grading software for use in clinical and epidemiological research. Clinical and Experimental Ophthalmology 41 (9) : 842-852. ScholarBank@NUS Repository. https://doi.org/10.1111/ceo.12112
Abstract: Background: To determine the reliability and agreement of a new optic disc grading software program for use in clinical, epidemiological research. Design: Reliability and agreement study. Samples: 328 monoscopic and 85 stereoscopic optic disc images. Methods: Optic disc parameters were measured using a new optic disc grading software (Singapore Optic Disc Assessment) that is based on polynomial curve-fitting algorithm. Two graders independently graded 328 monoscopic images to determine intergrader reliability. One grader regraded the images after 1 month to determine intragrader reliability. In addition, 85 stereo optic disc images were separately selected, and vertical cup-to-disc ratios were measured using both the new software and standardized Wisconsin manual stereo-grading method by the same grader 1 month apart. Intraclass correlation coefficient (ICC) and Bland-Altman plot analyses were performed. Main Outcome Measures: Optic disc parameters. Results: The intragrader and intergrader reliability for optic disc measurements using Singapore Optic Disc Assessment was high (ICC ranging from 0.82 to 0.94). The mean differences (95% limits of agreement) for intergrader vertical cup-to-disc ratio measurements were 0.00 (-0.12 to 0.13) and 0.03 (-0.15 to 0.09), respectively. The vertical cup-to-disc ratio agreement between the software and Wisconsin grading method was extremely close (ICC=0.94). The mean difference (95% limits of agreement) of vertical cup-to-disc ratio measurement between the two methods was 0.03 (-0.09 to 0.16). Conclusions: Intragrader and intergrader reliability using Singapore Optic Disc Assessment was excellent. This software was highly comparable with standardized stereo-grading method. Singapore Optic Disc Assessment is useful for grading digital optic disc images in clinical, population-based studies. © 2013 Royal Australian and New Zealand College of Ophthalmologists.
Source Title: Clinical and Experimental Ophthalmology
URI: http://scholarbank.nus.edu.sg/handle/10635/109084
ISSN: 14426404
DOI: 10.1111/ceo.12112
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

2
checked on Dec 18, 2018

WEB OF SCIENCETM
Citations

2
checked on Dec 18, 2018

Page view(s)

73
checked on Dec 14, 2018

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.