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Title: The prevalence and types of glaucoma in an urban Indian population: The Singapore Indian Eye Study
Authors: Narayanaswamy, A.
Baskaran, M.
Zheng, Y.
Lavanya, R.
Wu, R.
Wong, W.-L.
Saw, S.-M. 
Cheng, C.-Y. 
Wong, T.-Y. 
Aung, T.
Keywords: Epidemiology
Intraocular pressure
Issue Date: 2013
Citation: Narayanaswamy, A., Baskaran, M., Zheng, Y., Lavanya, R., Wu, R., Wong, W.-L., Saw, S.-M., Cheng, C.-Y., Wong, T.-Y., Aung, T. (2013). The prevalence and types of glaucoma in an urban Indian population: The Singapore Indian Eye Study. Investigative Ophthalmology and Visual Science 54 (7) : 4621-4627. ScholarBank@NUS Repository.
Abstract: PURPOSE. To determine the prevalence and types of glaucoma in an urban Singaporean Indian population. METHODS. The Singapore Indian Eye Study (SINDI) was a population-based, cross-sectional survey that examined 3400 (75.6% response) persons aged 40 to 80 years. Participants underwent a standardized examination including slit-lamp biomicroscopy, Goldmann applanation tonometry, and dilated optic disc assessment. Participants suspected to have glaucoma also underwent visual field examination (24-2 SITA standard, Humphrey Visual Field Analyzer II), gonioscopy, and repeat applanation tonometry. Glaucoma was defined according to International Society for Geographical and Epidemiologic Ophthalmology criteria. RESULTS. Of the 3400 participants, 78 (2.29%) had diagnosed glaucoma, giving an agestandardized prevalence of 1.95% (95% confidence interval [CI], 1.5%-2.5%). The agestandardized prevalence of primary open-angle glaucoma (POAG) was 1.25% (95% CI, 0.89%-1.73%), primary angle-closure glaucoma (PACG) 0.12% (95% CI, 0.04%-0.33%), and secondary glaucoma 0.55% (95% CI, 0.35%-0.86%). The mean IOP among the participants in the normal group in the study population was 15.6±2.6 mm Hg and 17.7±6.1 mm Hg in subjects with glaucoma (P = 0.003). The mean central corneal thickness (CCT) in the normal study population was 540.31±33.79; the mean CCT in subjects with POAG (529.8±30.8 lm) was statistically different from the normal study group (P = 0.003). CONCLUSIONS. The prevalence of glaucoma among Singaporean Indians 40 years of age and older in Singapore was 1.95%, approximately half that of the Chinese and the Malay persons in Singapore. As in other Asian studies, POAG was the main form of glaucoma accounting for nearly 60% of cases. © 2013 The Association for Research in Vision and Ophthalmology, Inc.
Source Title: Investigative Ophthalmology and Visual Science
ISSN: 01460404
DOI: 10.1167/iovs.13-11950
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