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|Title:||The impact of cataract, cataract types, and cataract grades on vision-specific functioning using rasch analysis|
|Citation:||Chew, M., Chiang, P.P.-C., Zheng, Y., Lavanya, R., Wu, R., Saw, S.M., Wong, T.Y., Lamoureux, E.L. (2012-07). The impact of cataract, cataract types, and cataract grades on vision-specific functioning using rasch analysis. American Journal of Ophthalmology 154 (1) : 29-38. ScholarBank@NUS Repository. https://doi.org/10.1016/j.ajo.2012.01.033|
|Abstract:||• PURPOSE: To determine the impact of cataracts and their types and grades on vision-specific functioning. • DESIGN: Prospective population-based cross-sectional study. • METHODS: The Singapore Indian Eye Study examined 3400 of 4497 (75.6% response rate) ethnic Indians 40 years of age and older living in Singapore. Three thousand one hundred sixty-eight (93.2%) fulfilled inclusion criteria with complete information for final analysis. Cataracts were assessed on slit-lamp examination and were graded according to the Lens Opacity Classification System III. Vision-specific functioning scores were explored with the Visual Function scale, validated using Rasch analysis. • RESULTS: Two hundred sixty-nine (8.5%) and 740 (23.4%) of the study participants had unilateral and bilateral cataracts, respectively, and 329 (10.4%), 800 (25.2%), and 128 (4.1%) participants had nuclear, cortical, and posterior subcapsular (PSC) cataracts, respectively. In multivariate linear regression models, the presence of bilateral rather than unilateral cataract (β = -0.12; 95% confidence interval, -0.20 to 0.00) was associated independently with poorer vision-specific functioning, even after adjusting for undercorrected refractive error (β = -0.11; 95% confidence interval, -0.21 to 0.00). Bilateral nuclear, cortical, and PSC cataracts also were associated with poorer vision-specific functioning (β = -0.31, -0.15, and -1.15, respectively), with combinations of them having even greater impact. Significantly poorer vision-specific functioning occurred at Lens Opacity Classification System grades 4 (nuclear opalescence), 5 (nuclear color), 3 (cortical), and 1 (PSC) or higher. • CONCLUSIONS: People with bilateral but not unilateral cataracts experience difficulty with performing vision-specific daily activities independent of refractive error, with PSC cataracts and cataract combinations having the greatest impact. Cataract types cause poorer vision-specific functioning beginning at different severity grades. © 2012 Elsevier Inc. All rights reserved.|
|Source Title:||American Journal of Ophthalmology|
|Appears in Collections:||Staff Publications|
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