Please use this identifier to cite or link to this item:
|Title:||Association between body mass index and cardiovascular disease mortality in east Asians and south Asians: Pooled analysis of prospective data from the Asia Cohort Consortium|
|Citation:||Chen, Y., Copeland, W.K., Vedanthan, R., Grant, E., Lee, J.E., Gu, D., Gupta, P.C., Ramadas, K., Inoue, M., Tsugane, S., Tamakoshi, A., Gao, Y.-T., Yuan, J.-M., Shu, X.-O., Ozasa, K., Tsuji, I., Kakizaki, M., Tanaka, H., Nishino, Y., Chen, C.-J., Wang, R., Yoo, K.-Y., Ahn, Y.-O., Ahsan, H., Pan, W.-H., Chen, C.-S., Pednekar, M.S., Sauvaget, C., Sasazuki, S., Yang, G., Koh, W.-P., Xiang, Y.-B., Ohishi, W., Watanabe, T., Sugawara, Y., Matsuo, K., You, S.-L., Park, S.K., Kim, D.-H., Parvez, F., Chuang, S.-Y., Ge, W., Rolland, B., McLerran, D., Sinha, R., Thornquist, M., Kang, D., Feng, Z., Boffetta, P., Zheng, W., He, J., Potter, J.D. (2013-10-05). Association between body mass index and cardiovascular disease mortality in east Asians and south Asians: Pooled analysis of prospective data from the Asia Cohort Consortium. BMJ (Online) 347 (7927) : -. ScholarBank@NUS Repository. https://doi.org/10.1136/bmj.f5446|
|Abstract:||Objective To evaluate the association between body mass index and mortality from overall cardiovascular disease and specific subtypes of cardiovascular disease in east and south Asians. Design Pooled analyses of 20 prospective cohorts in Asia, including data from 835 082 east Asians and 289 815 south Asians. Cohorts were identified through a systematic search of the literature in early 2008, followed by a survey that was sent to each cohort to assess data availability. Setting General populations in east Asia (China, Taiwan, Singapore, Japan, and Korea) and south Asia (India and Bangladesh). Participants 1 124 897 men and women (mean age 53.4 years at baseline). Main outcome measures Risk of death from overall cardiovascular disease, coronary heart disease, stroke, and (in east Asians only) stroke subtypes. Results 49 184 cardiovascular deaths (40 791 in east Asians and 8393 in south Asians) were identified during a mean follow-up of 9.7 years. East Asians with a body mass index of 25 or above had a raised risk of death from overall cardiovascular disease, compared with the reference range of body mass index (values 22.5-24.9; hazard ratio 1.09 (95% confidence interval 1.03 to 1.15), 1.27 (1.20 to 1.35), 1.59 (1.43 to 1.76), 1.74 (1.47 to 2.06), and 1.97 (1.44 to 2.71) for body mass index ranges 25.0-27.4, 27.5-29.9, 30.0-32.4, 32.5-34.9, and 35.0-50.0, respectively). This association was similar for risk of death from coronary heart disease and ischaemic stroke; for haemorrhagic stroke, the risk of death was higher at body mass index values of 27.5 and above. Elevated risk of death from cardiovascular disease was also observed at lower categories of body mass index (hazard ratio 1.19 (95% confidence interval 1.02 to 1.39) and 2.16 (1.37 to 3.40) for body mass index ranges 15.0-17.4 and|
|Source Title:||BMJ (Online)|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Mar 21, 2019
WEB OF SCIENCETM
checked on Mar 12, 2019
checked on Mar 1, 2019
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.