Please use this identifier to cite or link to this item:
|Title:||Similarities and differences in early retinal phenotypes in hypertension and diabetes|
retinal microvascular signs
|Citation:||Grosso, A., Cheung, N., Veglio, F., Wong, T.Y. (2011-09). Similarities and differences in early retinal phenotypes in hypertension and diabetes. Journal of Hypertension 29 (9) : 1667-1675. ScholarBank@NUS Repository. https://doi.org/10.1097/HJH.0b013e3283496655|
|Abstract:||The use of retinal photography in clinical practice and research has substantially increased the knowledge about the epidemiology, natural history and significance of diabetic and hypertensive retinopathy. Early retinopathy signs, including retinal microaneurysms, blot hemorrhages, cotton-wool spots and hard exudates, are common vascular abnormalities found in middle-aged to older people with diabetes and hypertension. The presence of these early retinopathy signs is associated with an increased risk of systemic vascular diseases, such as stroke, cognitive impairment, coronary heart disease, heart failure and nephropathy. These retinopathy lesions may therefore be considered as biomarkers of systemic microvascular processes caused by diabetes and hypertension. Nevertheless, whereas the interest in retinopathy assessment continues to grow, a core concept remains undefined: what is the relative importance and contribution of diabetes and hypertension in the development of early retinopathy signs? The answer of this fundamental question holds the key to better understanding of the systemic associations of early hypertensive and diabetic retinopathy. In this review, we summarize the similarities and differences of early retinopathy signs seen in diabetes and hypertension, and discuss the conceptual relevance from epidemiological, pathophysiological, and clinical perspectives. © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins.|
|Source Title:||Journal of Hypertension|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Jan 22, 2019
WEB OF SCIENCETM
checked on Jan 2, 2019
checked on Jan 18, 2019
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.