Please use this identifier to cite or link to this item: https://doi.org/10.1089/ars.2008.2412
Title: Resveratrol: Its biologic targets and functional activity
Authors: Pervaiz, S.
Holme, A.L. 
Issue Date: 1-Nov-2009
Citation: Pervaiz, S., Holme, A.L. (2009-11-01). Resveratrol: Its biologic targets and functional activity. Antioxidants and Redox Signaling 11 (11) : 2851-2897. ScholarBank@NUS Repository. https://doi.org/10.1089/ars.2008.2412
Abstract: The polyphenolic phytoalexin resveratrol (RSV) and its analogues have received tremendous attention over the past couple of decades because of a number of reports highlighting their benefits in vitro and in vivo in a variety of human disease models, including cardio- and neuroprotection, immune regulation, and cancer chemoprevention. These studies have underscored the high degree of diversity in terms of the signaling networks and cellular effector mechanisms that are affected by RSV. The activity of RSV has been linked to cell-surface receptors, membrane signaling pathways, intracellular signal-transduction machinery, nuclear receptors, gene transcription, and metabolic pathways. The promise shown by RSV has prompted heightened interest in studies aimed at translating these observations to clinical settings. In this review, we present a comprehensive account of the basic chemistry of RSV, its bioavailability, and its multiple intracellular target proteins and signaling pathways. Antioxid. Redox Signal. 11, 2851-2897. © 2009, Mary Ann Liebert, Inc.
Source Title: Antioxidants and Redox Signaling
URI: http://scholarbank.nus.edu.sg/handle/10635/108684
ISSN: 15230864
DOI: 10.1089/ars.2008.2412
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

266
checked on Sep 22, 2018

WEB OF SCIENCETM
Citations

247
checked on Sep 12, 2018

Page view(s)

50
checked on Sep 14, 2018

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.