Please use this identifier to cite or link to this item: https://doi.org/10.1371/journal.pbio.1001450
Title: Vesiclepedia: A Compendium for Extracellular Vesicles with Continuous Community Annotation
Authors: Kalra, H.
Simpson, R.J.
Ji, H.
Aikawa, E.
Altevogt, P.
Askenase, P.
Bond, V.C.
Borràs, F.E.
Breakefield, X.
Budnik, V.
Buzas, E.
Camussi, G.
Clayton, A.
Cocucci, E.
Falcon-Perez, J.M.
Gabrielsson, S.
Gho, Y.S.
Gupta, D.
Harsha, H.C.
Hendrix, A.
Hill, A.F.
Inal, J.M.
Jenster, G.
Krämer-Albers, E.-M.
Lim, S.K. 
Llorente, A.
Lötvall, J.
Marcilla, A.
Mincheva-Nilsson, L.
Nazarenko, I.
Nieuwland, R.
Nolte-'t Hoen, E.N.M.
Pandey, A.
Patel, T.
Piper, M.G.
Pluchino, S.
Prasad, T.S.K.
Rajendran, L.
Raposo, G.
Record, M.
Reid, G.E.
Sánchez-Madrid, F.
Schiffelers, R.M.
Siljander, P.
Stensballe, A.
Stoorvogel, W.
Taylor, D.
Thery, C.
Valadi, H.
van Balkom, B.W.M.
Vázquez, J.
Vidal, M.
Wauben, M.H.M.
Yáñez-Mó, M.
Zoeller, M.
Mathivanan, S.
Issue Date: Dec-2012
Citation: Kalra, H., Simpson, R.J., Ji, H., Aikawa, E., Altevogt, P., Askenase, P., Bond, V.C., Borràs, F.E., Breakefield, X., Budnik, V., Buzas, E., Camussi, G., Clayton, A., Cocucci, E., Falcon-Perez, J.M., Gabrielsson, S., Gho, Y.S., Gupta, D., Harsha, H.C., Hendrix, A., Hill, A.F., Inal, J.M., Jenster, G., Krämer-Albers, E.-M., Lim, S.K., Llorente, A., Lötvall, J., Marcilla, A., Mincheva-Nilsson, L., Nazarenko, I., Nieuwland, R., Nolte-'t Hoen, E.N.M., Pandey, A., Patel, T., Piper, M.G., Pluchino, S., Prasad, T.S.K., Rajendran, L., Raposo, G., Record, M., Reid, G.E., Sánchez-Madrid, F., Schiffelers, R.M., Siljander, P., Stensballe, A., Stoorvogel, W., Taylor, D., Thery, C., Valadi, H., van Balkom, B.W.M., Vázquez, J., Vidal, M., Wauben, M.H.M., Yáñez-Mó, M., Zoeller, M., Mathivanan, S. (2012-12). Vesiclepedia: A Compendium for Extracellular Vesicles with Continuous Community Annotation. PLoS Biology 10 (12) : -. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pbio.1001450
Abstract: Extracellular vesicles (EVs) are membraneous vesicles released by a variety of cells into their microenvironment. Recent studies have elucidated the role of EVs in intercellular communication, pathogenesis, drug, vaccine and gene-vector delivery, and as possible reservoirs of biomarkers. These findings have generated immense interest, along with an exponential increase in molecular data pertaining to EVs. Here, we describe Vesiclepedia, a manually curated compendium of molecular data (lipid, RNA, and protein) identified in different classes of EVs from more than 300 independent studies published over the past several years. Even though databases are indispensable resources for the scientific community, recent studies have shown that more than 50% of the databases are not regularly updated. In addition, more than 20% of the database links are inactive. To prevent such database and link decay, we have initiated a continuous community annotation project with the active involvement of EV researchers. The EV research community can set a gold standard in data sharing with Vesiclepedia, which could evolve as a primary resource for the field. © 2012 Kalra et al.
Source Title: PLoS Biology
URI: http://scholarbank.nus.edu.sg/handle/10635/108600
ISSN: 15449173
DOI: 10.1371/journal.pbio.1001450
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