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Title: C-reactive protein and microalbuminuria in a multi-ethnic Asian population
Authors: Sabanayagam, C.
Lee, J. 
Shankar, A.
Lim, S.C.
Wong, T.Y. 
Tai, E.S.
Keywords: Albuminuria
Kidney damage
Microvascular disease
Issue Date: Apr-2010
Source: Sabanayagam, C., Lee, J., Shankar, A., Lim, S.C., Wong, T.Y., Tai, E.S. (2010-04). C-reactive protein and microalbuminuria in a multi-ethnic Asian population. Nephrology Dialysis Transplantation 25 (4) : 1167-1172. ScholarBank@NUS Repository.
Abstract: Background. C-reactive protein (CRP), a marker for inflammation, has been recently associated with early kidney damage. We examined the association between CRP and micro/macroalbuminuria in a multi-ethnic Asian population using data from two population-based studies in Singapore.Methods. We studied 5127 individuals, who participated in two separate, cross-sectional studies, the Singapore Prospective Study Program [SP2]/Singapore Cardiovascular Cohort Study 2 (SCCS2), involving 4233 participants of Chinese, Malay and Indian ethnicity, aged 24-95 years in Singapore, and the Singapore Malay Eye Study (SiMES), involving 894 participants of Malay ethnicity, aged 40-80 years. Micro/macroalbuminuria was defined as urinary albumin-to-creatinine ratio of ≥17 mg/g for men and ≥25 g/g for women. CRP was analyzed as a continuous variable and as categories (3 mg/L).Results. The prevalence of micro/macroalbuminuria in the whole population was 21.1%. The prevalence increased with increasing categories of CRP. Compared with persons with CRP concentrations 3 mg/L; P trend
Source Title: Nephrology Dialysis Transplantation
ISSN: 09310509
DOI: ndt/gfp591
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