Please use this identifier to cite or link to this item:
|Title:||Assessment of iris surface features and their relationship with iris thickness in Asian eyes|
|Citation:||Sidhartha, E., Gupta, P., Liao, J., Tham, Y.-C., Cheung, C.Y., He, M., Wong, T.Y., Aung, T., Cheng, C.-Y. (2014). Assessment of iris surface features and their relationship with iris thickness in Asian eyes. Ophthalmology 121 (5) : 1007-1012. ScholarBank@NUS Repository. https://doi.org/10.1016/j.ophtha.2013.11.028|
|Abstract:||Purpose To assess iris surface features in Asian eyes and examine their associations with iris thickness measured by anterior segment optical coherence tomography (AS OCT). Design Cross-sectional study. Participants We recruited 250 subjects from the Singapore Malay Eye Study. Methods We obtained standardized slit-lamp photographs and developed a grading system assessing iris crypts (by number and size), furrows (by number and circumferential extent), and color (higher grade denoting darker iris). Vertical and horizontal cross-sections of the anterior chamber were imaged using AS OCT. Intragrader and intergrader agreements in the grading of iris surface were assessed by weighted κ (κw) statistic. Associations of the average iris thickness with the grade of iris features were assessed using linear regression analysis. Main Outcome Measures Frequency and size of iris crypts, furrows, and color; iris thickness at 750 μm (IT750) and 2000 μm (IT2000) from the scleral spur; and maximum iris thickness (ITM) averaged from the 4 quarters. Results Three hundred sixty-four eyes had complete and gradable data for crypts and color; 330 eyes were graded for furrows. The grading scheme showed good intragrader (crypt κw = 0.919, furrow κw =0.901, color κw = 0.925) and intergrader (crypt κw = 0.775, furrow κw = 0.836, color κw = 0.718) agreements. Higher crypt grade was associated independently with thinner IT750 (β [change in iris thickness per grade higher] = -0.007; P = 0.029), IT2000 (β = -0.018; P|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Oct 16, 2018
WEB OF SCIENCETM
checked on Oct 16, 2018
checked on Oct 12, 2018
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.