Please use this identifier to cite or link to this item: https://doi.org/10.3748/wjg.15.6096
Title: First endoscopic procedure for diagnosis and staging of mediastinal lymphadenopathy
Authors: Khoo, K.-L.
Ho, K.-Y. 
Khor, C.J.-L.
Nilsson, B.
Lim, T.-K. 
Keywords: Aspiration biopsy
Diagnosis
Endoscopy
Lung neoplasms
Lymphadenopathy
Mediastinum
Needle biopsy
Neoplasms staging
Ultrasound
Issue Date: 28-Dec-2009
Citation: Khoo, K.-L., Ho, K.-Y., Khor, C.J.-L., Nilsson, B., Lim, T.-K. (2009-12-28). First endoscopic procedure for diagnosis and staging of mediastinal lymphadenopathy. World Journal of Gastroenterology 15 (48) : 6096-6101. ScholarBank@NUS Repository. https://doi.org/10.3748/wjg.15.6096
Abstract: AIM: To compare a first diagnostic procedure of transbronchial needle aspiration (TBNA) with selection of endoscopic ultrasoundguided fineneedle aspiration (EUSFNA) or TBNA for mediastinal lymphadenopathy. METHODS: Sixty-eight consecutive patients with mediastinal lymphadenopathy on computed tomography (CT), who required cytopathological diagnosis, were recruited. The first 34 underwent a sequential approach in which TBNA was performed first, followed by EUSFNA if TBNA was unrevealing. The next 34 underwent a selective approach where either TBNA or EUS-FNA was selected as the first procedure based on the CT findings. RESULTS: The diagnostic yield of TBNA as the first diagnostic procedure in the sequential approach was 62%. In the selective approach, the diagnostic yield of the first procedure was 71%. There was no significant difference in the overall diagnostic yield, but there were significantly fewer combined procedures with the selective approach. CONCLUSION: Selecting either EUS-FNA or TBNA as the first diagnostic procedure achieved a comparable diagnostic yield with significantly fewer procedures than performing TBNA first in all patients. © 2009 The WJG Press and Baishideng. All rights reserved.
Source Title: World Journal of Gastroenterology
URI: http://scholarbank.nus.edu.sg/handle/10635/107940
ISSN: 10079327
DOI: 10.3748/wjg.15.6096
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