Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/107682
Title: Biomarkers: A molecular approach to cancer epidemiology
Authors: Shi, C.Y. 
Seow, A. 
Lin, Y. 
Chia, K.S. 
Ong, C.N. 
Chan, S.H. 
Lee, H.P. 
Keywords: Biological monitoring
Cancer aetiology
Genetic susceptibility
Oncogenes
Tumour suppressor genes
Issue Date: Jan-1996
Source: Shi, C.Y.,Seow, A.,Lin, Y.,Chia, K.S.,Ong, C.N.,Chan, S.H.,Lee, H.P. (1996-01). Biomarkers: A molecular approach to cancer epidemiology. Annals of the Academy of Medicine Singapore 25 (1) : 49-54. ScholarBank@NUS Repository.
Abstract: The rapidly evolving field of molecular epidemiology represents a paradigm shift in medical research, illustrating the convergence of basic, clinical and epidemiologic research, as well as the application of laboratory methods to population studies. As a complement and improvement to traditional epidemiologic approaches, the use of biomarkers offers more accurate exposure assessment at an individual level, better understanding of the biological mechanism of carcinogenesis by tracking a continuum of events between exposure and disease, as well as the ability to discern host or genetic factors that may account for variations in cancer susceptibility among individuals or ethnic populations. Further, biomarkers have also proved useful in cancer diagnosis and prognosis. This article attempts to review the latest progress in molecular cancer epidemiology and to summarise the current state of research in Singapore.
Source Title: Annals of the Academy of Medicine Singapore
URI: http://scholarbank.nus.edu.sg/handle/10635/107682
ISSN: 03044602
Appears in Collections:Staff Publications

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