Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/107678
Title: Human genome - From pieces to patterns
Authors: Sakharkar, M.K.
Kangueane, P.
Perumal, B.S.
Chow, V.T.K. 
Sorscher, E.
Sakharkar, K.R.
Hill, A.
Keywords: Block Length
Duplication
Exon-Intron Length Patterns
Gene Architecture
Genome Design
Human Genome
Issue Date: 2005
Source: Sakharkar, M.K.,Kangueane, P.,Perumal, B.S.,Chow, V.T.K.,Sorscher, E.,Sakharkar, K.R.,Hill, A. (2005). Human genome - From pieces to patterns. Frontiers in Bioscience 10 (SUPPL. 2) : 2576-2584. ScholarBank@NUS Repository.
Abstract: A profile of exon-intron lengths in genes shows a normal distribution. This observation suggests that different genes may have portions of their total exon and/or intron lengths in common. In order to explore the common exon-intron structural patterns that may arise due to common lengths across genes, we compared the exon-intron length patterns of annotated human genes. We discovered 1762278 conserved arrangements of exon-intron length across the otherwise unrelated and diverse genomic landscape. The existence of common exon-intron length patterns across unrelated genes suggests for their role of in gene assemblage and human genome design and architecture.
Source Title: Frontiers in Bioscience
URI: http://scholarbank.nus.edu.sg/handle/10635/107678
ISSN: 10939946
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

Page view(s)

19
checked on Dec 7, 2017

Google ScholarTM

Check


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.