Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/107677
Title: Intron position conservation across eukaryotic lineages in tubulin genes
Authors: Perumal, B.S.
Sakharkar, K.R.
Chow, V.T.K. 
Kangueane, P.
Sakharkar, M.K.
Keywords: Conservation
Genome Evolution
Intron Gain
Intron Loss
Tubulin
Issue Date: 2005
Source: Perumal, B.S.,Sakharkar, K.R.,Chow, V.T.K.,Kangueane, P.,Sakharkar, M.K. (2005). Intron position conservation across eukaryotic lineages in tubulin genes. Frontiers in Bioscience 10 (SUPPL. 1) : 2412-2419. ScholarBank@NUS Repository.
Abstract: A compilation of intron positions obtained from a large number of eukaryotic genomes across orthologous tubulins is explored for molecular evolution. Comparison of intron positions for 41 α, 80 β, and 30 γ tubulin genomic sequences indicates that the putative ancestral tubulin gene contained at least 19, 33, and 52 intron positions distributed at different sites in the coding regions for α, β, and γ tubulins, respectively. Many intron positions are old and are conserved across different eukaryotic lineages and intron distribution patterns are consistent with 'introns-early' hypothesis.
Source Title: Frontiers in Bioscience
URI: http://scholarbank.nus.edu.sg/handle/10635/107677
ISSN: 10939946
Appears in Collections:Staff Publications

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