Please use this identifier to cite or link to this item: https://doi.org/10.1002/biot.201100237
Title: Microfabricated particulate drug-delivery systems
Authors: Pan, J.
Chan, S.Y. 
Lee, W.G.
Kang, L. 
Keywords: Engineered drug delivery
Particle shape
Particle size
Issue Date: Dec-2011
Citation: Pan, J., Chan, S.Y., Lee, W.G., Kang, L. (2011-12). Microfabricated particulate drug-delivery systems. Biotechnology Journal 6 (12) : 1477-1487. ScholarBank@NUS Repository. https://doi.org/10.1002/biot.201100237
Abstract: Micro- and nanoparticulate drug-delivery systems (DDSs) play a significant role in formulation sciences. Most particulate DDSs are scaffold-free, although some particles are encapsulated inside other biomaterials for controlled release. Despite rapid progress in recent years, challenges still remain in controlling the homogenicity of micro-/nanoparticles, especially for two crucial factors in particulate DDSs: the size and shape of the particles. Recent approaches make use of microfabrication techniques to generate micro-/nanoparticles with highly controllable architectures free of scaffolds. This review presents an overview of a burgeoning field of DDSs, which can potentially overcome some drawbacks of conventional techniques for particle fabrication and offer better control of particulate DDSs. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Source Title: Biotechnology Journal
URI: http://scholarbank.nus.edu.sg/handle/10635/106678
ISSN: 18606768
DOI: 10.1002/biot.201100237
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