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|Title:||Micro- and nanoscale technologies for tissue engineering and drug discovery applications|
|Citation:||Chung, B.G., Kang, L., Khademhosseini, A. (2007-12). Micro- and nanoscale technologies for tissue engineering and drug discovery applications. Expert Opinion on Drug Discovery 2 (12) : 1653-1668. ScholarBank@NUS Repository. https://doi.org/10.1517/174604220.127.116.113|
|Abstract:||Micro- and nanoscale technologies are emerging as powerful enabling tools for tissue engineering and drug discovery. In tissue engineering, micro- and nanotechnologies can be used to fabricate biomimetic scaffolds with increased complexity and vascularization. Furthermore, these technologies can be used to control the cellular microenvironment (i.e., cell-cell, cell-matrix and cell-soluble factor interactions) in a reproducible manner and with high temporal and spatial resolution. In drug discovery, miniaturized platforms based on micro- and nanotechnology can be used to precisely control the fluid flow, enable high-throughput screening, and minimize sample or reagent volumes. In addition, these systems enhance reproducibility and significantly reduce reaction times. This paper reviews the recent developments in the field of micro- and nanoscale technology and gives examples of their tissue engineering and drug discovery applications. © 2007 Informa UK Ltd.|
|Source Title:||Expert Opinion on Drug Discovery|
|Appears in Collections:||Staff Publications|
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