Please use this identifier to cite or link to this item: https://doi.org/10.1517/17460441.2.12.1653
Title: Micro- and nanoscale technologies for tissue engineering and drug discovery applications
Authors: Chung, B.G.
Kang, L. 
Khademhosseini, A.
Keywords: Drug discovery
Microfluidic
Nanotechnology
Surface patterning
Tissue engineering
Issue Date: Dec-2007
Citation: Chung, B.G., Kang, L., Khademhosseini, A. (2007-12). Micro- and nanoscale technologies for tissue engineering and drug discovery applications. Expert Opinion on Drug Discovery 2 (12) : 1653-1668. ScholarBank@NUS Repository. https://doi.org/10.1517/17460441.2.12.1653
Abstract: Micro- and nanoscale technologies are emerging as powerful enabling tools for tissue engineering and drug discovery. In tissue engineering, micro- and nanotechnologies can be used to fabricate biomimetic scaffolds with increased complexity and vascularization. Furthermore, these technologies can be used to control the cellular microenvironment (i.e., cell-cell, cell-matrix and cell-soluble factor interactions) in a reproducible manner and with high temporal and spatial resolution. In drug discovery, miniaturized platforms based on micro- and nanotechnology can be used to precisely control the fluid flow, enable high-throughput screening, and minimize sample or reagent volumes. In addition, these systems enhance reproducibility and significantly reduce reaction times. This paper reviews the recent developments in the field of micro- and nanoscale technology and gives examples of their tissue engineering and drug discovery applications. © 2007 Informa UK Ltd.
Source Title: Expert Opinion on Drug Discovery
URI: http://scholarbank.nus.edu.sg/handle/10635/106676
ISSN: 17460441
DOI: 10.1517/17460441.2.12.1653
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