Please use this identifier to cite or link to this item: https://doi.org/10.1111/j.1524-4733.2008.00361.x
Title: Validity, feasibility and acceptability of time trade-off and standard gamble assessments in health valuation studies: A study in a multiethnic Asian population in Singapore
Authors: Wee, H.-L.
Li, S.-C. 
Xie, F.
Zhang, X.-H.
Luo, N.
Feeny, D.
Cheung, Y.-B.
MacHin, D.
Fong, K.-Y.
Thumboo, J.
Keywords: Asia
Attitude to death
Comparative study
Quality of life
Social values
Value of life
Issue Date: Mar-2008
Citation: Wee, H.-L., Li, S.-C., Xie, F., Zhang, X.-H., Luo, N., Feeny, D., Cheung, Y.-B., MacHin, D., Fong, K.-Y., Thumboo, J. (2008-03). Validity, feasibility and acceptability of time trade-off and standard gamble assessments in health valuation studies: A study in a multiethnic Asian population in Singapore. Value in Health 11 (SUPPL. 1) : S3-S10. ScholarBank@NUS Repository. https://doi.org/10.1111/j.1524-4733.2008.00361.x
Abstract: Objectives: To assess the validity, feasibility and acceptability of standard gamble (SG) and time trade-off (TTO) assessments in a multiethnic Asian population. Methods: Through in-depth interviews performed among Chinese, Malay, and Indian Singaporeans (education ≥ 6 years), we assessed validity of SG/TTO methods for eliciting health preferences by hypothesizing that 1) SG/TTO scores for three hypothetical health states (HS) would exhibit ranked order (decreasing scores with worse HS); and 2) more subjects would rate the most severe HS as worse than dead. Subjects also evaluated feasibility and acceptability of SG/TTO using a 10-point visual analog scale (VAS) and open-ended questions. Ratings were compared using Kruskal-Wallis, Wilcoxon signed-rank tests or tests of proportions. Results: Validity: In 62 subjects (90% response rate), as hypothesized, SG and TTO scores exhibited ranked order with increasing HS severity (SG: 0.85, 0.08, -19.00; TTO: 0.85, 0.00, -0.18). More subjects rated the most severe HS as worse than dead (SG: 8%, 39%, 59%; TTO: 8%, 45% and 62%). Feasibility: Subjects felt SG and TTO were easy to understand (median VAS scores: 8.0 vs. 8.0, P = 0.87) and to complete (8.0 vs. 8.0, P = 0.84). Acceptability: SG and TTO were well accepted, with TTO less so than SG (median [interquartile range] offensiveness: 2.0 [0, 4.0] vs. 2.0 [0, 3.0], P = 0.045). Overall, subjects did not have a clear preference for SG/TTO (50% vs. 45%, P = 0.70). Conclusions: This study suggests the validity, feasibility and acceptability of SG and TTO for population-based HS valuation studies in a multiethnic Asian population. © 2008, International Society for Pharmacoeconomics and Outcomes Research (ISPOR).
Source Title: Value in Health
URI: http://scholarbank.nus.edu.sg/handle/10635/106548
ISSN: 10983015
DOI: 10.1111/j.1524-4733.2008.00361.x
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