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| Title: | Synthesis and structural studies of (2-oxo-2,3-dihydroimidazo[1,2-a]pyridin-3-yl)acetic acids | Authors: | Dolzhenko, A.V. Kolotova, N.V. Kozminykh, V.O. Chui, W.-K. Heng, P.W.S. Khrustalev, V.N. |
Issue Date: | 1-Jan-2004 | Citation: | Dolzhenko, A.V.,Kolotova, N.V.,Kozminykh, V.O.,Chui, W.-K.,Heng, P.W.S.,Khrustalev, V.N. (2004-01-01). Synthesis and structural studies of (2-oxo-2,3-dihydroimidazo[1,2-a]pyridin-3-yl)acetic acids. Heterocycles 63 (1) : 55-62. ScholarBank@NUS Repository. | Abstract: | (2-Oxo-2,3-dihydroimidazo[1,2-a]pyridin-3-yl)acetic acids (4a-c, 9a-c) were prepared from 2-aminopyridines by acylation with maleic or citraconic anhydrides and followed by Michael addition. Formation of 3-methyl substituted derivatives (9a-c) from citraconic anhydride was found to be regioselective. The molecular conformations of the products in the solution and in the crystal form were discussed based on 1H NMR spectral and X-Ray data. | Source Title: | Heterocycles | URI: | http://scholarbank.nus.edu.sg/handle/10635/106398 | ISSN: | 03855414 |
| Appears in Collections: | Staff Publications |
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