Please use this identifier to cite or link to this item: http://scholarbank.nus.edu.sg/handle/10635/106398
Title: Synthesis and structural studies of (2-oxo-2,3-dihydroimidazo[1,2-a]pyridin-3-yl)acetic acids
Authors: Dolzhenko, A.V.
Kolotova, N.V.
Kozminykh, V.O.
Chui, W.-K. 
Heng, P.W.S. 
Khrustalev, V.N.
Issue Date: 1-Jan-2004
Source: Dolzhenko, A.V.,Kolotova, N.V.,Kozminykh, V.O.,Chui, W.-K.,Heng, P.W.S.,Khrustalev, V.N. (2004-01-01). Synthesis and structural studies of (2-oxo-2,3-dihydroimidazo[1,2-a]pyridin-3-yl)acetic acids. Heterocycles 63 (1) : 55-62. ScholarBank@NUS Repository.
Abstract: (2-Oxo-2,3-dihydroimidazo[1,2-a]pyridin-3-yl)acetic acids (4a-c, 9a-c) were prepared from 2-aminopyridines by acylation with maleic or citraconic anhydrides and followed by Michael addition. Formation of 3-methyl substituted derivatives (9a-c) from citraconic anhydride was found to be regioselective. The molecular conformations of the products in the solution and in the crystal form were discussed based on 1H NMR spectral and X-Ray data.
Source Title: Heterocycles
URI: http://scholarbank.nus.edu.sg/handle/10635/106398
ISSN: 03855414
Appears in Collections:Staff Publications

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