Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.tetlet.2010.10.170
Title: Synthesis and potent cytotoxic activity of 8- and 9-anilinophenanthridine- 7,10-diones
Authors: Bernardo, P.H.
Khanijou, J.K.
Lam, T.H.
Tong, J.C.
Chai, C.L.L. 
Keywords: Anticancer
Michael addition
Quinones
SRB assay
Issue Date: 5-Jan-2011
Source: Bernardo, P.H., Khanijou, J.K., Lam, T.H., Tong, J.C., Chai, C.L.L. (2011-01-05). Synthesis and potent cytotoxic activity of 8- and 9-anilinophenanthridine- 7,10-diones. Tetrahedron Letters 52 (1) : 92-94. ScholarBank@NUS Repository. https://doi.org/10.1016/j.tetlet.2010.10.170
Abstract: A series of 8-anilino and 9-anilinophenanthridine-7,10-diones was prepared and screened against various cancer cell lines to measure anti-proliferative activity. The compounds tested display potent cytotoxic activity in the micromolar and sub-micromolar range. These compounds are promising new leads for developing anticancer compounds. © 2010 Elsevier Ltd. All rights reserved.
Source Title: Tetrahedron Letters
URI: http://scholarbank.nus.edu.sg/handle/10635/106397
ISSN: 00404039
DOI: 10.1016/j.tetlet.2010.10.170
Appears in Collections:Staff Publications

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