Please use this identifier to cite or link to this item: https://doi.org/10.1002/adsc.201200020
Title: Iron-catalyzed efficient synthesis of amides from aldehydes and amine hydrochloride salts
Authors: Ghosh, S.C.
Ngiam, J.S.Y.
Chai, C.L.L. 
Seayad, A.M.
Dang, T.T.
Chen, A.
Keywords: aldehydes
amidation
amides
amine salts
catalysis
iron(II) sulphate
Issue Date: 21-May-2012
Source: Ghosh, S.C., Ngiam, J.S.Y., Chai, C.L.L., Seayad, A.M., Dang, T.T., Chen, A. (2012-05-21). Iron-catalyzed efficient synthesis of amides from aldehydes and amine hydrochloride salts. Advanced Synthesis and Catalysis 354 (8) : 1407-1412. ScholarBank@NUS Repository. https://doi.org/10.1002/adsc.201200020
Abstract: A practical and efficient method for the synthesis of amides has been developed by iron-catalysed oxidative amidation of aldehydes with amine hydrochloride salts. A wide range of amides have been obtained in good to excellent yields under mild conditions. The application of this novel amide formation reaction to the synthesis of pharmaceutical compounds has been successfully demonstrated. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Source Title: Advanced Synthesis and Catalysis
URI: http://scholarbank.nus.edu.sg/handle/10635/106091
ISSN: 16154150
DOI: 10.1002/adsc.201200020
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