Please use this identifier to cite or link to this item: https://doi.org/10.3390/pharmaceutics3040731
Title: Development of re-usable yeast-gellan gum micro-bioreactors for potential application in continuous fermentation to produce bio-ethanol
Authors: Tan, S.M.
Heng, P.W.S. 
Chan, L.W. 
Keywords: Bioethanol
Gellan gum
Micro-bioreactors
Microencapsulation
Water-in-oil emulsion
Issue Date: Dec-2011
Source: Tan, S.M.,Heng, P.W.S.,Chan, L.W. (2011-12). Development of re-usable yeast-gellan gum micro-bioreactors for potential application in continuous fermentation to produce bio-ethanol. Pharmaceutics 3 (4) : 731-744. ScholarBank@NUS Repository. https://doi.org/10.3390/pharmaceutics3040731
Abstract: The objectives of this study were to investigate the feasibility of encapsulating yeast cells using gellan gum by an emulsification method and to evaluate the fermentation efficiency and the reusability of the micro-bioreactors produced. It was found that yeast cells could be successfully encapsulated to form relatively spherical micro-bioreactors with high specific surface area for mass transfer. Cell viability was found to be reduced by one log reduction after the emulsification process. The ethanol yield of the micro-bioreactors was comparable to that of free yeast in the first fermentation cycle. The micro-bioreactors remained intact and could be re-used up to 10 cycles of fermentation. Despite cell breakthrough, relatively high ethanol yields were obtained, indicating that the micro-bioreactors also functioned as regenerative reservoirs of yeast. © 2011 by the authors; licensee MDPI, Basel, Switzerland.
Source Title: Pharmaceutics
URI: http://scholarbank.nus.edu.sg/handle/10635/105831
ISSN: 19994923
DOI: 10.3390/pharmaceutics3040731
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