Please use this identifier to cite or link to this item:
|Title:||Cross-linking mechanisms of calcium and zinc in production of alginate microspheres|
|Authors:||Chan, L.W. |
|Citation:||Chan, L.W., Jin, Y., Heng, P.W.S. (2002-08-21). Cross-linking mechanisms of calcium and zinc in production of alginate microspheres. International Journal of Pharmaceutics 242 (1-2) : 255-258. ScholarBank@NUS Repository. https://doi.org/10.1016/S0378-5173(02)00169-2|
|Abstract:||Calcium chloride and zinc sulphate were used to cross-link alginate microspheres prepared by an emulsification method. The microspheres cross-linked by a combination of these two salts showed different morphology and slower drug release compared with those cross-linked by the calcium salt alone. From viscosity study, it was found that zinc cations interacted with the alginate molecules to a greater extent than calcium cations. The varying effects of the salts on the properties of the microspheres were largely attributed to their ability to interact with the alginate molecules. © 2002 Elsevier Science B.V. All rights reserved.|
|Source Title:||International Journal of Pharmaceutics|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Jun 14, 2018
WEB OF SCIENCETM
checked on May 9, 2018
checked on Jun 1, 2018
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.