Please use this identifier to cite or link to this item:
|Title:||Antimalarial activity of ferrocenyl chalcones|
|Citation:||Wu, X., Wilairat, P., Go, M.-L. (2002-09-02). Antimalarial activity of ferrocenyl chalcones. Bioorganic and Medicinal Chemistry Letters 12 (17) : 2299-2302. ScholarBank@NUS Repository. https://doi.org/10.1016/S0960-894X(02)00430-4|
|Abstract:||A series of ferrocenyl chalcones were synthesized and evaluated for in vitro antimalarial activity against a chloroquine-resistant strain of Plasmodium falciparum. The most active compounds were 1-(3-pyridyl)-3-ferrocenyl-2-propen-1-one (6) and 1-ferrocenyl-3-(4-nitrophenyl)-2-propen-1-one (28) with IC50 of 4.5 and 5.1 μM, respectively. Differences in activity were not readily explained by the size and lipophilicity characteristics of these compounds. © 2002 Elsevier Science Ltd. All rights reserved.|
|Source Title:||Bioorganic and Medicinal Chemistry Letters|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on May 21, 2018
WEB OF SCIENCETM
checked on May 1, 2018
checked on May 11, 2018
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.